Clinical Fertility Services
in Flowood, MS
Mississippi Reproductive Medicine assists women and men with fertility problems as well as female endocrine disorders, uterine abnormalities, endometriosis, uterine fibroids, and a number of related health concerns.
We get to the root cause of infertility and provide ways to treat it.
Infertility is diagnosed as the inability to successfully become pregnant after 12 months of unprotected intercourse or after 6 months of unprotected intercourse if 35 years of age or older. Mississippi Reproductive Medicine assesses your needs and provides treatment for those diagnosed with infertility.
Approximately 1/3 of infertility causes are related to female, 1/3 are related to male, and the remaining 1/3 are a combination of both male and female factors.
Ovulation induction is done with oral and /or injectable medications. This treatment often corrects ovulation disorders and is a very common treatment for infertility and often used as a “first line” therapy. Oral ovulation medications (ie Clomid, Letrozole ) are generally well tolerated by most women.
Intrauterine insemination (IUI) is a common and relatively low-cost procedure that can help couples achieve pregnancy.
Sperm is collected and processed to obtain the best quality sperm from a semen sample and then placed into the uterus via a simple office procedure. IUI can be performed with fresh or frozen sperm. Sperm can be obtained from the male partner or from a sperm donor. MRM works with several sperm banks and once a sample is chosen, we can accept shipment to use whenever the patient is ready for an IUI.
IUI is one of the more common procedures performed in our clinic. There is little to no “down time” and the patient is able to return to daily activities without any limitations practically immediately after the procedure. An IUI generally requires one ultrasound, a “trigger injection” followed by the intrauterine insemination one to two days later.
Egg Freezing (Oocyte Cryopreservation)
Many women are considering oocyte cryopreservation. It may be recommended for a woman facing upcoming gonadotoxic therapy (ie cancer treatment) and if this is the case, the staff of MRM is available to evaluate a patient in this case 7 days a week. If you are facing a cancer diagnosis and subsequent treatment, time is of the essence and we are here to see you either same day or within one day of your diagnosis and treatment plan from your oncologist.
If considering elective oocyte cryopreservation for social/personal reasons (ie career, educational demands or relationship concerns) MRM provides this service as well. Elective oocyte cryopreservation is becoming more common as many women take a more proactive role in their future reproductive autonomy.
Embryo Testing (Preimplantation Genetic Testing or PGT)
Preimplantation Genetic Testing (PGT) is an option for patients going through IVF. PGT is performed to determine if the chromosomes of the embryo(s) are normal (euploid) versus abnormal (aneuploid). Embryos with too few or too many chromosomes, if transferred, will most often result in a failure to achieve pregnancy or in a miscarriage. PGT can also be used to identify specific genetic abnormalities of the embryo(s), such as cystic fibrosis or sickle cell disease. PGT is performed by removing a few cells from the trophectoderm (outer layer of the embryo which becomes the placenta). The embryo is then safely cryopreserved in our laboratory for transfer at a later time once the results are reviewed.
Some patients may elect the use of a donated embryo. These embryos were previously created during an IVF cycle at MRM and later “donated” if not used by the original intended parents. Embryo donation at MRM is primarily done in an anonymous fashion; however, embryos can be directly donated by request. A person most likely to benefit from the use of a donor embryo may be one that requires both a donor egg and donor sperm, or possibly one that has recurrent pregnancy loss or IVF failure with their own gametes, or possibly someone looking to keep IVF costs to a minimum.
When surgical intervention is deemed necessary, the staff of MRM provides these services without needing additional referrals. Surgical procedures often performed include laparoscopy, hysteroscopy, laparotomy, or a combination of the above. The majority of surgery cases are performed on an out-patient basis and the patient is able to return to normal daily activities within a few days. Surgery may be needed for endometriosis, correction of pelvic adhesions, resection of uterine fibroids or polyps, removal of ovarian cysts, removal or repair of damaged fallopian tube(s), correction of uterine or vaginal septum (or other uterine abnormalities), or even the correction of previously ligated fallopian tubes (tubal anastomosis).
Female Endocrine Disorders
While endocrine disorders account for a smaller percentage of infertility cases, the staff of MRM is knowledgeable in the management and treatment of a wide variety of disorders affecting the reproductive system, including delayed puberty, hyperprolactinemia, hirsutism, polycystic ovarian syndrome (PCOS), hypothalamic amenorrhea, and premature ovarian failure.
Muellerian anomalies including uterine didelphys, bicornuate uterus, and septate uterus, can contribute to reproductive dysfunction. Often these anomalies are undetected until an infertility evaluation is completed. The most common evaluation of uterine anomalies is through the use of an office sonohystogram (SHG) or an office hysterosalpingogram (HSG). Both evaluation options are available at MRM and are office-based procedures with no downtime, little to no discomfort, and both take less than 30 minutes to complete. Both are safe, efficient, convenient and diagnostic for uterine abnormalities.
Recurrent Pregnancy Loss (RPL)
Approximately 5% of couples experience the loss of two or more pregnancies. Recurrent pregnancy loss can be attributed to chromosomal disorders, endocrine disorders, coagulation disorders, luteal phase defects, and/or uterine anomalies. A complete RPL evaluation is started in the office through initial labwork and pelvic evaluation. The most reassuring news with RPL is that most couples who suffer from RPL will eventually maintain a successful pregnancy.
Fibroids or uterine myoma may be causes of bleeding, pain, infertility and recurrent pregnancy loss. As with other uterine abnormalities, fibroids can be diagnosed with an SHG, HSG, office hysteroscopy, or even a complete gynecological ultrasound only. Depending on the size and location of fibroids, the MRM staff will decide if surgical, medical, or even no therapy is indicated or required.
Endometriosis is a cause of both pain and infertility. Endometriosis is a common finding of patients affected with infertility. Endometriosis can be treated both medically and surgically. Depending on the patient’s future reproductive plans, the better treatment will be determined. Many patients benefit from the surgical evaluation and treatment of endometriosis prior to conception.
Ovarian reserve refers to your egg supply. Because we cannot count your eggs we use our testing to estimate your egg supply. This estimate is based on several factors, such as age, follicular phase hormone values and reproductive history. An ultrasound will be done to count the small (antral) follicles in each ovary and a hormonal blood analysis will be done at the same time.
An HSG is an X-ray test used to view your reproductive organs. HSG is performed in the clinic and is a safe, effective and efficient way to assess the patency of fallopian tubes and the shape of the uterine cavity. An HSG can identify blockage of the fallopian tubes, adhesions or scarring of the fallopian tubes or uterus, and other issues which can affect your fertility ( fibroids, uterine anomalies, etc ). An HSG has little “downtime” and can be performed in less than 15 minutes.